Tumor Suppressor

The Guardians of the Genome. Discover genes that protect your cells from uncontrolled growth and repair DNA damage.

Tumor Suppressors: Your Internal Security Service

Our body consists of trillions of cells that are constantly dividing. In this highly complex process, errors in the genetic code can occur. Tumor suppressor genes act as the most important control instance: they recognize damaged DNA, initiate repair processes or, in extreme cases, trigger programmed cell death (apoptosis) so that no degenerated cells can multiply.

security

TP53 is often called the "Guardian of the Genome". It is the most frequently mutated gene in human cancers. A functional TP53 gene ensures that cells with significant DNA damage stop dividing until the damage is repaired.

efficiency

BRCA1 and BRCA2 are specialized in repairing double-strand breaks in DNA. While mutations in these genes increase the risk for certain cancers, modern medicine offers specialized screening and prevention strategies for carriers.

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Worth Knowing

Genetics is not fate. Knowing your predisposition allows you to get the best out of your biology through a targeted lifestyle.

Gene Profiles in this Category

BRCA1

Gene Profile

BRCA1

BRCA1 is a tumor suppressor gene that plays a crucial role in DNA repair and maintaining genomic stability….

Analysis Details →

TP53

Gene Profile

TP53

TP53 encodes the p53 protein, one of the most important tumor suppressors, often called the ‘guardian of the genome’….

Analysis Details →

BRCA2

Gene Profile

BRCA2

BRCA2 is another important tumor suppressor gene, closely related to BRCA1 and playing a similar role in DNA repair….

Analysis Details →

Frequently Asked Questions

Does a mutation in a tumor suppressor gene mean I will get cancer?

No. It means an increased susceptibility because one of the "security systems" is less efficient. Many other factors like environment, lifestyle and other genes play a role.

Can I strengthen my tumor suppressor genes?

The DNA sequence itself is fixed. However, a healthy lifestyle (no smoking, UV protection, antioxidant-rich diet) reduces the number of "attacks" on your DNA, relieving the work of these genes.

What is the difference between an oncogene and a tumor suppressor?

Think of a car: Oncogenes are like the accelerator (when mutated, they get stuck and push cell division). Tumor suppressors are the brakes (when they fail, the cell can't stop dividing).