All Articles Tagged As: mice

Evolution Of Human Genome's 'Guardian' Gives People Unique Protections From DNA Damage (1/21/2008)

Human evolution has created enhancements in key genes connected to the p53 regulatory network -- the so-called guardian of the genome -- by creating additional safeguards in human genes to boost the network's ability to guard against DNA damage that could cause cancer or a variety of genetic diseases, an international team of scientists led by Cincinnati Children's Hospital Medical Center writes in the Jan. 22 Proceedings of the National Academy of Sciences. Because genetically engineered mouse models are increasingly powerful tools in understanding the risks and mechanisms of human diseases -- and rodents do not have the same evolution-based safeguards in p53 function as humans -- the study also underscores the need for additional considerations in the interpretation of research using rodent models. ...> Full Article

Ultraconserved Elements in the Genome: Are They Indispensable? (9/6/2007)

Three years ago, "ultraconserved elements" were discovered in the genomes of mice, rats, and humans. These are DNA sequences 200 base pairs in length or longer — some are over 700 base pairs long — showing 100-percent identity among the three species. They have been perfectly conserved since the last common ancestor of mice, rats, and humans, which lived some 85 million years ago. ...> Full Article

Interaction Of Just Two Genes Governs Coloration Patterns In Mice (8/16/2007)

Biologists at Harvard University and the University of California, San Diego, have found that a simple interaction between just two genes determines the patterns of fur coloration that camouflage mice against their background, protecting them from many predators. The work, published recently in the journal PLoS Biology, marks one of the few instances in which specific genetic changes have been linked to an organism's ability to survive in the wild. ...> Full Article

Genes Affect Aggression In Mice Species (5/24/2007)

Imagine if a naturally occurring chemical in your body could help make you feel more calm and relaxed - but it would only work during the long days of summer. ...> Full Article

Discovery Of Gene Mutation That Causes Infertility In Male Mice Gives Promise Of Similar Finding In Infertile Men (4/12/2007)

Discovery of gene mutation that causes infertility in male mice gives promise of similar finding in infertile men ...> Full Article

To recognize their friends, mice use their amygdalas (4/11/2007)

Even those who can’t remember names can usually recall faces. New research from Rockefeller University suggests that a simple brain chemical, a neuropeptide called oxytocin, is a reason. ...> Full Article