All Articles Tagged As: genetic disorders
Investigators Say Findings May Impact Treatment of Additional Diseases
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New research has found that many of the symptoms of fragile X syndrome, the most common cause of inherited mental retardation, can be eliminated in mice by reducing the expression of a single gene in the brain. The study suggests that the gene is a prime target for drugs to alleviate symptoms of the disorder, for which there is currently no specific treatment.
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When the genetic material inside a cell's nucleus starts to fall apart, a protein called ATM takes charge and orchestrates the rescue mission. Surprisingly, for ATM to kick into full gear, the stretches of DNA flanking a chromosomal break are just as important as the damaged site itself, report scientists at the Salk Institute for Biological Studies.
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Children with Tourette's syndrome may have to put up with some unwanted movement and verbal tics, but neuroscientists at Georgetown University Medical Center and the Kennedy Krieger Institute have found that they are much quicker at processing certain mental grammar skills than are children without the disorder.
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