All Articles Tagged As: gene expression
ArrayExpress, the publicly available database of transcriptomics data at the European Molecular Biology Laboratory's European Bioinformatics Institute [EMBL-EBI], has doubled in size in 2007, reaching the 100,000-hybridisation milestone. The database now holds snapshots of gene expression [identifying which genes are specifically expressed in a particular tissue or in response to a drug, for example] for more than 180 species under thousands of experimental conditions.
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 | Researchers report a breakthrough in understanding how plants perceive and respond to light. ...> Full Article |
 | One gene for pea pod color generates green pods while a variant of that gene gives rise to the yellow-pod phenotype, a feature that helped Gregor Mendel, the 19th century Austrian priest and scientist, first describe genetic inheritance. However, many modern-day geneticists are focused on the strange ability of some genes to be expressed spontaneously in either of two possible ways. ...> Full Article |
The observation that males evolve more quickly than females has been around since 19th century biologist Charles Darwin noted the majesty of a peacock's tail feather in comparison with the plainness of the peahen's.
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When ancient retroviruses slipped bits of their DNA into the primate genome millions of years ago, they successfully preserved their own genetic legacy. Today an estimated 8 percent of the human genetic code consists of endogenous retroviruses (ERVs)--the DNA remnants from these so-called 'selfish parasites.'
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 | Fruit fly genomes provide window to genome function, clues for mammal studies ...> Full Article |
When are the genes adventuresome, and when are they conservative?
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 | Using a novel "deep sequencing" technology that can in one fell swoop decode 50 million sequences representing well over a billion bases of DNA, a research team led by University of Delaware scientists is working to unmask where, why and how certain genes are switched on or off in rice--a crop vital to the world's food supply. ...> Full Article |
Building a comprehensive microRNA expression atlas is not easy. Just ask the Rockefeller University scientists who, in a massive collaborative effort involving 50 investigators from six countries, led the project. In three years, they catalogued microRNA expression patterns in more than 250 healthy and diseased cell and tissue samples - human and rodent - from 26 different organ systems, and in the process discovered several dozen new microRNAs as well.
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 | Scientists have discovered a pattern in the DNA sequence of the mouse genome that may play a fundamental part in the way DNA molecules regulate gene expression. The research, led by Emory University scientists along with colleagues at Jacobs University, Bremen, Germany, will be published in the Aug. 22 Advance Online publication of the journal Nature. ...> Full Article |
 | Findings indicate alternative splicing is highly regulated ...> Full Article |
 | Duke researchers found variances in two major traits when they compared gene regulation in chimps, humans and rhesus macaques ...> Full Article |
It is not just what's in your genes, it's how you turn them on that accounts for the difference between species - at least in yeast - according to a report by Yale researchers in this week's issue of Science.
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 | Researchers at North Carolina State University have received a five-year, $1.4 million grant from the National Institutes of Health (NIH) to develop a series of "photo-switchable" compounds that will allow scientists to turn individual genes on and off within zebrafish embryos, enabling them to determine the function of particular genes. ...> Full Article |
Experiments in animals have provided additional and tantalizing evidence that what a pregnant mother eats can make her offspring more susceptible to disease later in life.
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Investigators at St. Jude Children's Research Hospital have discovered how a single molecular "on switch" triggers gene activity that might cause effects ranging from learning and memory capabilities to glucose production in the liver.
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 | Could a baby's early diet be setting it up for a lifetime of problems? New research by the Faculty of Kinesiology suggests that infants who receive a high fat, high protein diet could alter the way their body and metabolism work later in life, making them more susceptible to certain chronic diseases and conditions. ...> Full Article |
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