All Articles Tagged As: cancer
 | Human evolution has created enhancements in key genes connected to the p53 regulatory network -- the so-called guardian of the genome -- by creating additional safeguards in human genes to boost the network's ability to guard against DNA damage that could cause cancer or a variety of genetic diseases, an international team of scientists led by Cincinnati Children's Hospital Medical Center writes in the Jan. 22 Proceedings of the National Academy of Sciences. Because genetically engineered mouse models are increasingly powerful tools in understanding the risks and mechanisms of human diseases -- and rodents do not have the same evolution-based safeguards in p53 function as humans -- the study also underscores the need for additional considerations in the interpretation of research using rodent models. ...> Full Article |
 | Bacteria that cause tumours in plants modify plant genomes by skilfully exploiting the plants' first line of defence. ...> Full Article |
Cells have the remarkable ability to keep track of their genetic contents and - when things go wrong - to step in and repair the damage before cancer or another life-threatening condition develops.
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 | The arboreal, branch-swinging antics of the gibbon are nothing compared to the acrobatics its genome has undergone during evolution. While the genomes of humans and other primates still resemble that of their common ancestor, the massive genomic scrambling of the gibbon genome has rendered it a complex puzzle. Solving that puzzle, scientists believe, could help reveal how evolution experiments with genomic rearrangement, as well as how chromosomes can become unstable in cancer and other genetic diseases. ...> Full Article |
Study uses ‘histone code’ for functional genome annotation
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